Throughout the body blood flow is regulated by vascular tone secondary to local or neurologic control. However, in the musculoskeletal system, the effects of muscular contraction can lead to augmentation of restriction of local blood flow. While repetitive muscle contraction incr [....] » Read More
Globally, hypertension is the number one risk factor for death, affecting more than 1 billion people. Hypertension is the result of the interactions among genetics, epigenetics, environment, and lifestyle. The long-term regulation of blood pressure (BP) rests on renal and non-ren [....] » Read More
Dyslipidaemia comprises of abnormal lipid components and refers mainly to increased levels of LDL, non HDL particles and triglycerides while decreased levels of HDL Dyslipidaemia is a common and independent modifiable risk fac [....] » Read More
In this study, we explore the possibility that ECG recordings belong to class of multifractal process for which a large number of scaling exponents are required to characterize their scaling structures. We use the BIDMC Congestive Heart Failure database including long term ECG re [....] » Read More
Peripheral artery disease (PAD) is a cardiovascular disease affecting more than 8.5 million Americans over the age of 40 years and is prevalent in the geriatric cardiology population. PAD is a manifestation of systemic atherosclerosis, characterized by atherosclerotic blockages o [....] » Read More
The pursuit of cardiovascular wellness is of paramount global concern, touching the lives of many individuals and societies. Understanding the intricate interplay between economics and behavior in the context of heart health is pivotal for crafting effective strategies to mitigat [....] » Read More
Exercise is an important factor of rehabilitation in heart failure patients, improving several indicators of disease prognosis and functional capacity. The aim of the present study was to examine the effect of a cardiorespiratory rehabilitation program on the physical and mental [....] » Read More
Introduction Congestive heart failure (CHF) is an increasingly prevalent terminal illness in a globally aging population. Despite optimal medical management, prognosis remains poor – a fact seldom communicated to patients and/or their families. Evidence suggests nume [....] » Read More
Atherosclerosis, the leading cause of cardiovascular diseases, is driven by high blood cholesterol levels and chronic inflammation. The disruption of the hepatic interaction between Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) and Low-Density Lipoprotein Receptor (LDLR) downr [....] » Read More
Neovascularization of the ischemic myocardium following infarction is vital for the survival of cardiomyocytes and prevention of heart failure. However, the intrinsic revascularization following ischemic injury in the heart is inadequate to restore blood flow to the infarcted myo [....] » Read More
Most palpitations in pregnancy are benign and usually occur due to atrial or ventricular premature complexes. Careful consideration should be given to the gestation stage and the patient's hemodynamic state. In hemodynamically stable pregnant patients with acute onset of [....] » Read More
Background: Arrhythmias are one of the most serious disorders in cardiovascular and clinical medicine. Understanding the pathogenesis and mechanisms of arrhythmias is very advantageous to the appropriate management and treatment of all arrhythmia types. The “Graded phenomen [....] » Read More
Title : Managing total chronic coronary occlusion: Noninvasive External Counterpulsation (ECP) induces collaterogenesis, relieving ischemia, as demonstrated by quantitative PET myocardial perfusion imaging: ECP is a cost-effective alternative to high risk PCI
Michael E Merhige, State University of NY at Buffalo, United States
Background: External Counter Pulsation (ECP) is an FDA approved, noninvasive, treatment for patients with refractory angina, who are not candidates for low-risk interventional revascularization, such as those with chronic total coronary occlusion (CTO). ECP uses sequentially infl [....] » Read More
Title : Novel signaling pathways and therapeutic options for pulmonary hypertension
Yong Xiao Wang, Albany Medical Center, United States
Pulmonary hypertension (PH) is a common and devastating lung disease. The current primary medications for this disease are to use non-specific vasodilators, but patients do not always respond well to non-specific vasodilators. Voltage-dependent potassium channels and store-operat [....] » Read More
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model to be set up through biodesign-inspired and biotech-driven translational applications and cardiology-related marketing to secure the human healthcare and biosafety
Sergey Suchkov, Institute for Biotech & Global Health of RosBiotech and A.I. Evdokimov MGMSU, Russian Federation
A new systems approach to diseased states and wellness result in a new branch in the healthcare ser-vices, namely Personalized and Precision Medicine (PPM). To achieve the implementation of PPM concept, it is necessary to create a fundamentally new strategy based upon the re [....] » Read More
Title : Clinical pharmacology of sotagliflozin – Novel quality in treatment of heart failure
Miroslav Radenkovic, University of Belgrade, Serbia
Heart failure is a serious clinical syndrome with symptoms and signs provoked by a structural and functional cardiac abnormality, and coupled with elevated natriuretic peptide levels and evident pulmonary or systemic congestion. Regardless of outstanding improvements in the manag [....] » Read More
Title : Antibodies with functionality as a new generation of translational tools designed to monitor autoimmune myocarditis at clinical and subclinical stages
Sergey Suchkov, Institute for Biotech & Global Health of RosBiotech and A.I. Evdokimov MGMSU, Russian Federation
Catalytic Abs (catAbs) are multivalent immunoglobulins (Igs) with a capacity to hydrolyze the antigenic (Ag) substrate. In this sense, proteolytic Abs (Ab-proteases) represent Abs to provide proteolytic effects. Autoimmune myocarditis (AIM) can be defined as the autoimmune inf [....] » Read More
Title : Cuffless blood pressure monitoring using multiple artificial intelligence models
Prabode Weebadde, Purdue University, United States
In the U.S., every year, about 800,000 people die due to cardiovascular diseases (CVD) or diseases related to the heart and blood vessels. Of those 800,000, 650,000 deaths were related to the heart, and 150,000 were related to blood vessels. To put it in another perspective, ever [....] » Read More
Title : Antiphospholipid antibodies as independent predictors of cardiovascular failure: Multidisciplinary approach is the key to the success
Ljudmila Stojanovich, University of Belgrade, Serbia
Introduction: A major cause of morbidity and mortality in the context of the antiphospholipid syndrome (APS) is the occurrence of thrombotic events, including cardiac involvement. Methods: We investigated 585 patients: 404 pts with PAPS followed up for an average of 44.00&plus [....] » Read More
Title : Preliminary research of the application of resting myocardial contrast echocardiography multi-indicator combined diagnostic model in coronary heart disease
Xin Li, Chinese PLA General Hospital-Sixth Medical Center, China
Objective This article is in purpose of developing a multi-indicator combined diagnostic model of resting myocardial contrast echocardiography (MCE) to qualify myocardial perfusion dysfunction in coronary heart disease (CHD). Methods We performed resting MCE and stre [....] » Read More
Title : The potential of Machine learning to predict the arterial stiffness from hemodynamics and biomechanics parameters
Asma Ayadi, Tunisian Center for Nuclear Sciences and Technology, Tunisia
Arterial stiffness has emerged as a prominent marker of risk for cardiovascular disease. Few studies are interested in predicting symptomatic or asymptomatic arterial stiffness from hemodynamics and biomechanics parameters. Machine learning models can be used as an intelligent to [....] » Read More
Title : Unlocking mysteries: MINOCA's unexpected faces.
Ajay Anil Bagalkot, Aarupadai Veedu Medical College and Hospital, Pondicherry, India
MI with non-obstructive coronary arteries (MINOCA) is precipitated secondary to a group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impai [....] » Read More
Title : Role of Micro RNAs 204 and 210 in the diagnosis of pulmonary arterial hypertension and distinguishing between idiopathic, systemic sclerosis and schistosomiasis associated pulmonary arterial hypertension.
Mark Onsy Dimitry, National Research Centre, Egypt
Background: Pulmonary arterial hypertension (PAH) is an uncommon disease and according to the Sixth International Symposium on Pulmonary Hypertension (PH) it is defined as an increase in mean pulmonary arterial pressure >20 mmHg with normal left ventricular filling pressures a [....] » Read More
Title : Clinical evaluation of common oxygenators used in cardiopulmonary bypass and physical laws related to them
Motahareh Ghodrati, Shahid Beheshti hospital, Iran (Islamic Republic of)
Many improvements have been made for the CPB device since the early 1950s. The design and construction of oxygenators is based on three basic components: the mechanism for blood circulation, the method of gas exchange of oxygen and carbon dioxide, and the mechanism for temperatur [....] » Read More
Title : Correlation between B line in lung ultrasound and plasma NT-proBNP level in patients with acute heart failure
Jahanara Arzu, Bangabandhu Sheikh Mujib Medical University, Bangladesh
Acute heart failure (AHF) is a major cause of morbidity and mortality worldwide. Although this is a common cause of dyspnoea, its diagnosis still represents a challenge. Lung ultrasound (LUS) is an emerging point-of-care diagnostic tool. Objective: The aim of the study was to ass [....] » Read More
Title : Compaired sacubitril/valsartan with benalapril on the left ventricular remordeling of AMI after PPCI : A case-control study
Yanmin xu, Tian Jin Medical university , China
Background: To compare the effect of sacubitril/valsartan with benalapril on left ventricular remodeling in patients with acute myocardial infarction. Materials and Methods: 85 patients with acute ST segment elevation myocardial infarction who were treated with PCI in the Seco [....] » Read More