Title : Clinical evaluation of common oxygenators used in cardiopulmonary bypass and physical laws related to them
Many improvements have been made for the CPB device since the early 1950s. The design and construction of oxygenators is based on three basic components: the mechanism for blood circulation, the method of gas exchange of oxygen and carbon dioxide, and the mechanism for temperature control. Manufacturers focus on two factors of patient safety (for example, using a bubble trap, impregnating the bypass circuit and less prime volume) and increasing performance (for example, transferring gases and exchanges) to provide the desired product. The strategy of companies to provide the best product is different. For example, some oxygenators are high pressure to improve gas transfer and gas microemboli, and others are low pressure to reduce damage to blood cells. While all products have minimum standards. In this discussion, we reviewed the basic principles of physics and reviewed studies with the aim of clinical evaluation of oxygenators in the field of gas exchange, prime volume, pressure difference and hematology.
Audience Take Away
- Basic principles of physics: The article discuss the basics of physics such as mass and pressure, which are relevant in understanding the design and construction of oxygenators.
- Blood circulation: The article discuss the importance of blood circulation and how it relates to the performance and safety of oxygenators.
- Gas exchange of oxygen and carbon dioxide: You learn about the different ways that companies are designing their oxygenators to improve gas exchange of oxygen and carbon dioxide.
- Strategies of different companies: You learn about the different strategies that companies are using to provide the best oxygenators, such as focusing on improving gas transfer, or reducing damage to blood cells.
- Clinical evaluation of oxygenators: You learn about how clinical evaluation of oxygenators is important in determining their effectiveness and safety.