Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting millions worldwide. While catheter ablation is a well-established treatment for AF, it carries risks of complications such as pulmonary vein stenosis (PVS) and esophageal injury. Pulse field ablation (PF [....] » Read More
Ischemic Heart Failure usually occurs due to delayed treatment of coronary artery disease. Rapidly worsening ischemic heart failure can occur due to Acute onset STEMI in a patient with critical multi vessel coronary artery disease with or without previously compromised left ventr [....] » Read More
Ischemic heart failure (IHF), primarily resulting from Coronary Artery Disease, remains a significant cause of morbidity and mortality globally. Surgical revascularization, particularly off- pump coronary artery bypass grafting (CABG), is a cornerstone treatment for patients with [....] » Read More
Coronary artery bypass grafting (CABG) remains a cornerstone for advanced coronary artery disease (CAD), but long-term success is closely linked to patients’ adherence to recommended lifestyle modifications. Optimizing perioperative care through nutritional management is in [....] » Read More
Vericiguat is a novel oral soluble guanylate cyclase (sGC) stimulator used in the treatment of heart failure with reduced ejection fraction (HFrEF). It belongs to a new class of medications that enhance the cyclic guanosine monophosphate (cGMP) pathway, which plays a crucial role [....] » Read More
Background: A compromised cardiac autonomic reactivity with an impaired left ventricular ejection fraction (LVEF) leads to increased mortality and morbidity in post myocardial infarction (MI) patients. We examined the combination of autonomic profile parameters with LVEF for pred [....] » Read More
Introduction: Diseases of the heart valves constitute a major cause of cardiovascular morbidity and mortality worldwide with an enormous burden on healthcare resources(1). The dominant form of heart disease in the developing nations is Rheumatic heart disease (RHD)(2). The preval [....] » Read More
Background: A prospective comparative study was conducted at our institution comparing the left ventricular myocardial interstitial fibrosis in two groups of patients with Rheumatic mitral valve stenosis (Wilkins score <8 vs >10) analyzing the ventricular tissue biopsy [....] » Read More
Peripheral artery disease (PAD) is a prevalent but underrecognized atherosclerotic disease that carries a powerful prognostic weight. Lower extremity PAD affects an estimated 8.5 million Americans over age 40 and roughly 202 million people globally. In India, PAD prevalence is si [....] » Read More
Introduction: Bacterial infection leads to the activation of CALC—1 gene and production of PCT in all parenchymal tissues in response to bacterial infection. Most tissues, except the thyroid gland C-cells and some neuro-endocrine tissues, lack the ability to cleave PCT to i [....] » Read More
Background: Cardiovascular diseases (CVDs) remain the leading global cause of mortality, with a significant proportion attributable to modifiable behavioral and metabolic risk factors. In India, the rising burden of CVD among working-age adults highlights the need for preventive [....] » Read More
Sternotomy has been the most common approach for the correction of congenital cardiac defects, and questions arise surrounding the safety, feasibility, and cost-effectiveness of implementing minimally invasive techniques in congenital cardiac surgery, despite their global adoptio [....] » Read More
Minimally invasive cardiac surgery has entered a new era, propelled by advances in robotics and Artificial Intelligence (AI). This presentation explores how these technologies are reshaping surgical care across the full patient continuum—from preoperative planning to intrao [....] » Read More
Uniportal Video Assisted Thoracoscopic Surgeries (UVATS) have advantage of making Thoracic Surgery minimally invasive without compromising on outcome. VATS was initially performed through multiple ports but in patients with dense adhesions and complex locations many times accurat [....] » Read More
Objective: Coronary artery bypass grafting (CABG) via sternotomy is the standard and conventional procedure for patients with multivessel coronary artery disease. Minimally invasive coronary artery bypass grafting (MICS CABG) via left thoracotomy has become an alternative procedu [....] » Read More
Constrictive pericarditis is an uncommon but serious complication of lung transplantation, marked by pericardial fibrosis and impaired diastolic filling. It can lead to significant morbidity if not recognized and treated early. This case highlights a rare instance of constrictive [....] » Read More
Objective: Aortic dissection is closely associated with inflammation. Currently, red blood cell distribution width (RDW) has been regarded as a novel inflammatory biomarker. The role of RDW on the prognosis of patients with Type A aortic dissection after surgery still remains unc [....] » Read More
Streptococcus agalactiae, commonly known as Group B strep (GBS), is an uncommon pathogen in most adults and is typically only seen in pregnant women and neonates. Local and systemic complications from GBS typically have a high mortality rate, with infective endocarditis (IE) bein [....] » Read More
Background: According to a study conducted in 2020 there is a prevalence of .2% of the general population living with Postural Orthostatic Tachycardia Syndrome. However, due to the covid-19 pandemic, rates of diagnosis are on the rise and therefore there are increased discussions [....] » Read More
Background: Mitral regurgitation (MR) is a prevalent valvular heart disease associated with significant morbidity and mortality. While surgical mitral valve repair or replacement remains the gold standard, transcatheter mitral valve repair (TMVR) using the MitraClip has emerged a [....] » Read More
Background: Fractional Flow Reserve (FFR) is the gold standard for guiding percutaneous coronary intervention (PCI) by assessing the hemodynamic significance of coronary lesions. However, its use is limited by the need for hyperemic agents, leading to increased procedural time an [....] » Read More
Introduction: Hypertension (HTA) is a major risk factor for cardiovascular diseases. Spontaneously hypertensive rats (SHR) serve as a genetic model that mimics the characteristics of human disease. Female SHR generally exhibit lower blood pressure (BP) than their male count [....] » Read More
Oncological diseases are the second most common cause of death among adults worldwide after cardiovascular diseases (CVD). In clinical practice, comorbidity of cancers and CVD is increasingly registered, which certainly increases the risk of death. The main cause of death in pati [....] » Read More
Lipoprotein (a) [Lp(a)] is a unique lipoprotein particle composed of an LDL-like particle linked to a glycoprotein called apolipoprotein(a). Elevated levels of Lp(a) have been identified as an independent risk factor for cardiovascular disease, including atherosclerosis, heart at [....] » Read More
Direct myocardial transplantation of HFDSCs (Fetal Liver Stem Cells) by open-chest surgical procedure was performed in 10 patients with HF due to nonischemic, nonchagasic dilated cardiomyopathy. All 10 patients survived the operation. At 40 months, the mean (+/-SD) NYHA class dec [....] » Read More
Nanomedicine, or the use of materials with at least one dimension less than 100 nm, has led to improved disease prevention, diagnosis, and treatment. This talk will cover recent advances in the use of nanomaterials to prevent, diagnose, and treat cardiovascular diseases. Specific [....] » Read More
Background: The association between plasma free fatty acid (FFA) and the outcomes in the heart failure (HF) patients remains unclear. Methods: A cohort study among HF patients was performed. Plasma FFA was analyzed as both a continuous and a categorical variable (grouped by te [....] » Read More
Classic orthostatic hypotension (OH) is a common geriatric disorder and is associated with cardiovascular risk. There are so far too few data available on the prognostic importance of initial OH and the comparison with sustained OH. This study investigated cardiovascular outcomes [....] » Read More
Human immunodeficiency virus (HIV) has direct and indirect effects on both bone marrow cells and cardiomyocytes. The common pathogenetic process unites the formation of pancytopenia and chronic heart failure (CHF) in HIV-infected patients. Pathogenesis of haematological disorders [....] » Read More
Left Ventricular (LV) Rupture after Mitral Valve Replacement is a serious complication and carries a very high mortality. Fortunately it is not common but nevertheless it can happen without any warning and catch the surgeon off guard. Various manoeuvres are available to prevent t [....] » Read More
Introduction: To compare autologous versus non-autologous transfusion in patients undergoing CABG and its early outcomes. This study seeks to evaluate the impact of different transfusion strategies on key postoperative outcomes, including morbidity and mortality. Methodology: [....] » Read More
Effective communication is at the heart of quality patient care, especially in cardiology, where complex medical decisions can significantly impact patient outcomes. This speech addresses the critical role of communication between cardiologists and patients in enhancing cardiac c [....] » Read More
Background: Coronary artery disease (CAD) results from the obstruction of blood supply to the heart. Angioplasty is a common intervention for managing CAD, supplemented by supportive and preventive therapies. Modifiable risk factors for CAD include hypertension, diabetes, dy [....] » Read More
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide. Modern pharmacology offers a variety of treatments, yet the rising prevalence of CVDs necessitates alternative and complementary strategies. Nature, with its vast repository of medicinal pl [....] » Read More
Composite textile stents with core-shell structure have been developed. Biodegradable polyvinyl alcohol (PVA) yarns are twisted and then coated with polycaprolactone/polyethylene glycol (PEG) blends. The coated yarns are weft knitted into braids and then thermally treated to form [....] » Read More
Although the regulation of cholesterol homeostasis in the body has been extensively studied, there is little information on how this regulation takes place in the brain. Cholesterol does not cross the blood-brain barrier; therefore cholesterol metabolism in the brain is independe [....] » Read More
Introduction: Electrocardiogram (ECG) interpretation plays an immense clinical role for the diagnosis of coronary heart disease. But its interpretation remains a challenging task for junior medical staffs. Einthoven applied vectors to discuss the cardiac electrical activity even [....] » Read More
Introduction: Atrial fibrillation (AF) is one of the most common and probable serious arrhythmia and a hallmark of an increasing risk of pathological thrombus formation. Interestingly, normal sinus rhythm (NSR) is the standard rhythm in a normal person. The sino-atrial node (SAN) [....] » Read More
Kinetic modeling is an essential method in understanding the dynamic interactions of biological systems, particularly in the context of cardiovascular physiology. This study delves into the application of kinetic modeling to elucidate the heart's function as a critical input [....] » Read More
Annually, approximately 2,500 – 3000 patients in the United States receive left ventricular assist devices (LVADs), making it increasingly likely that healthcare providers and EMS will encounter cardiac emergencies in this population. Cardiopulmonary resuscitation (CPR) in [....] » Read More
Heart disease is the leading cause of death worldwide effecting both men and women, however gender disparities are present in the diagnosis, treatment and even clinical outcomes. Clinical trials in cardiovascular disease have predominantly focused on male patients. Women with hea [....] » Read More
Throughout the body blood flow is regulated by vascular tone secondary to local or neurologic control. However, in the musculoskeletal system, the effects of muscular contraction can lead to augmentation or restriction of local blood flow. While repetitive muscle contraction incr [....] » Read More
Genetic heart diseases are common causes of sudden cardiac death (SCD) in the young and are typically divided into inherited cardiomyopathies and primary electrical heart diseases. Cardiomyopathies associated with the risk of SCD include hypertrophic cardiomyopathy (HCM) and arrh [....] » Read More
Introduction: Diseases such as acute coronary syndromes (ACS), with signs such as difficulty breathing when exerting effort or chest pain at rest, are frequently expressed in patients with coronary artery diseases (CAD). The percentage of patients with myocardial ischemia without [....] » Read More
Chronic pain is defined as persistent pain for more than three months and can be classified as primary with no known etiology, or secondary pertinent to a pathological process and specific clinical diagnosis. In previous studies, we observed that it directly impacts cardiac rehab [....] » Read More
The APN functions as the patient advocate, the care facilitator and the optimizer of the patient’s hospital journey and experience. Areas of practice: Advanced knowledge and experience in the management of implanted cardiac devices, optimizing their function, enabl [....] » Read More
Cardiovascular diseases, particularly myocardial infarction (MI), remain a major global health challenge. Recent studies have highlighted the cardioprotective potential of sodium-glucose co-transporter 2 (SGLT2) inhibitors, originally developed for managing glycemia in diabetes. [....] » Read More
Introduction: Sickle Cell Disease (SCD) is the most common inherited hemoglobinopathy, marked by chronic hemolytic anemia and vaso-occlusion due to a mutation in the β-globin gene. This leads to multi-organ damage and increased risk for cardiopulmonary complications, includi [....] » Read More
Title : The development of human relaxin-2 for heart failure with preserved ejection fraction, HFpEF
Thomas Bernd Dschietzig, Relaxera GmbH & Co. KG, Germany
Human relaxin-2 (hRlx-2) is a hormone of pregnancy that has engendered a great deal of interest as a therapy for various cardiovascular and inflammatory diseases, among them Acute Heart Failure and Systemic Scleroderma. Here, we propose and summarize data showing that Rlx-2 repre [....] » Read More
Title : Innovative mechanisms, consequences and therapeutics for pulmonary hypertension
Yong Xiao Wang, Albany Medical College, United States
Currently, pulmonary hypertension (PH) is a widespread lung disease, molecular mechanisms remain poorly understanded, and medications are neither always effective nor specific. In a series of our present studies, we have explored the potential important role of ryanodine receptor [....] » Read More
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through bio design-driven translational applications and cardiology-related marketing to secure the human healthcare and biosafety
Sergey Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, Personalized and Precision Medicine (PPM). To achieve the implementation of PPM concept, it is necessary to create a fundamentally new strategy based upon the recogni [....] » Read More
Title : Clinical pharmacology of sotatercept - The novel quality advancement in biological therapy of pulmonary arterial hypertension
Miroslav Radenkovic, University of Belgrade, Serbia
Pulmonary arterial hypertension (PAH) remains a debilitating disease with high morbidity and mortality. It is a rare, progressive and ultimately life-threatening disease in which blood vessels in the lungs thicken and narrow, causing significant strain on the heart. Patients with [....] » Read More
Title : A decade of DCD heart transplantation utilising normothermic machine perfusion in Australia
Claudio Soto, St Vincent's Hospital, Australia
The use of donation after circulatory death (DCD) donors for heart transplantation represents a relatively new entry into efforts made to help expand the donor pool. The use of Normothermic Machine Perfusion (NMP) through the Transmedics Organ Care System Heart (OCS Heart) allows [....] » Read More
Title : Application of minimally invasive surgical techniques in pericardial and macrovascular diseases associated with infectious diseases
Jintang He, Kunming Third People's Hospital, China
Objective: Infectious diseases are still a serious public health problem in the world. Millions of people die from infectious diseases every year, and cardiovascular events account for a very important proportion. Through the treatment of infectious diseases (tuberculosis) in our [....] » Read More
Title : Mechanical valve for isolated mitral stenoses complicated massive thromboses of left atrium: Is it necessary?
Valery Boukarim, Amosov National Institute of Cardiovascular Surgery, Ukraine
Objective: To analyzed main problems in surgery of mitral valve diseases (MVD) complicated by left atrium`s massive thromboses (LAMT) (thromboses more than 1/3 of left atrium`s volume). Materials and Methods: 336 adult patients (pts) with MVD complicated LAMT were consequtive [....] » Read More
Title : Paravetebral block with liposomal bupivacaine for enhanced recovery in open thoracotomy: A case report
Vivek Vaibhav, Rama Medical College Hospital and Research Center, India
A 77-year-old Female patient underwent an open thoracotomy for lung B/L breast cancer. Preoperative PVB was performed at the T5-T7 levels, using a combination of liposomal bupivacaine and standard bupivacaine for both intraoperative anesthesia and postoperative pain relief. [....] » Read More
Title : Antibodies with functionality as a new generation of translational tools designed to monitor autoimmune myocarditis at clinical and subclinical stages
Sergey Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Catalytic Abs (catAbs) are multivalent immunoglobulins (Igs) with a capacity to hydrolyze the antigenic (Ag) substrate. In this sense, proteolytic Abs (Ab-proteases) represent Abs to provide proteolytic effects. Abs against Cardiac Myosin (CM) with proteolytic activity exhibiting [....] » Read More
Title : Cardiac surgery in patients with low ejection fraction
Nuruddin Mohammod Zahangir, Green Life Medical College Hospital, Bangladesh
Objective: To see the outcome of cardiac surgery in patients with low ejection fraction. Methods: We retrospectively reviewed 2382 cardiac surgery cases from 11.6.17 to 24.3.25. Among them CABG was performed in 2278 (95.63%) patients in this patient’s group 1 [....] » Read More
Title : A rare case of slow flow mimicking acute coronary syndrome
Nidhish Niranjan Nisty, Nisty Heart Centre, India
Introduction: The coronary slow flow phenomenon is an important, angiographic entity characterized by delayed progression of the injected contrast medium through the coronary tree. The clinical implications are significant, with over 80% of patients experiencing recurrent chest p [....] » Read More
Title : The role of activity trackers in monitoring health and progress in individuals with chronic diseases
Praveen Veerabhadrappa, Penn State University, United States
Activity trackers, also known as fitness trackers or wearable health devices, have revolutionized the way people monitor their physical activity and overall health. These devices, which include popular brands like Fitbit, Apple Watch, and Garmin, are equipped with sensors that me [....] » Read More
Title : Automated assessment of atrial septal defects using deep learning
Zhang Xin, Capital Medical University, China
Aim: Atrial septal defect (ASD) is a typical cardiac defect in the atrial septum, which accounts for around 10% of congenital heart disease (CHD). The early diagnosis and treatment of ASD are crucial to avoid serious complications. Conventional pre-treatment assessment methods to [....] » Read More
Title : Double-chambered left ventricle - From clinical to basic
Fangyun Wang, Capital Medical University, China
Introduction: Double-chambered left ventricle (DCLV) is a particularly rare congenital cardiovascular malformation that is difficult to diagnose. It is characterized by the subdivision of the left ventricle into two chambers by an abnormal septum or muscle band. Compared to [....] » Read More
Title : Diagnosis and prognosis of abnromal origin of coronary arteries
Ma Ning, Capital Medical University, China
Objective: To investigate the diagnostic and prognostic value of echocardiography in patients with anomalous origin of the coronary arteries(AOCA),and to analyze its diagnostic accuracy and impact on patient outcomes. Methods: A retrospective analysis was conducted on clinical [....] » Read More
Title : Mitral-aortic-tricuspid valve correction in CPB complicated with small cavity of left ventricle
Volodymyr Popov, NICVS Amosova, Ukraine
Aim: To determine significance of patient-prosthesis mismatch (PPM) (indexed effective orifice area <1,2 cm²/m²) after combined mitral-aortic valve replacement (MAVR) + TV`s plasty (TV) in pts with small cavity of left ventricle (SCLV) (end-diastolic volume (EDV) &le [....] » Read More
Title : Association between endothelial dysfunction assessed by Reactive Hyperemia Index (LnRHI) and diabetes mellitus in heart transplant recipients
Armele Dornelas de Andrade, Federal University of Pernambuco, Brazil
Background: Endothelial dysfunction (ED) is a key factor in cardiovascular disease and is commonly observed in heart transplant (HTx) recipients. The reactive hyperemia index (LnRHI) is a validated, noninvasive marker of ED. Diabetes mellitus (DM), a well-established risk factor [....] » Read More
Title : Determinants of arterial compliance and vascular resistance in healthy children and adolescents
Maria da Gloria Rodrigues Machado, Faculty of Medical Sciences of Minas Gerais, Brazil
Backgroud: Early exposure to cardiovascular risk factors during childhood is associated with impaired arterial distensibility, as well as other vascular alterations, suggesting that biomarkers of vascular aging can be used to identify children and adolescents at risk. Reduced ar [....] » Read More
Title : The management of hypercholesteremia with lipid lowering therapy inclisiran
Kalpesh Patel, Barts Health NHS Trust, United Kingdom
Increasing prevalence of cardiovascular disease leading to events such as myocardial infarction requires aggressive management of secondary prevention therapy. Lipid lowering treatments which target low density lipoprotein (LDL-C) requires advanced treatment strategies in additio [....] » Read More
Title : Association of arterial stiffness and changes in intrinsic capacity through the locomotion domain in elderly people in primary care
Maria da Gloria Rodrigues Machado, Faculty of Medical Sciences of Minas Gerais, Brazil
Aging is one of the risk factors for cardiovascular diseases. In particular, excessive pulsatility is associated with microvascular lesions in high-flow organs, such as the brain and kidney, suggesting that small vessels are damaged. On the other hand, intrinsic capacity (IC) is [....] » Read More