Design of textile biodegradable composite stent having core shell structure

Title : Design of textile biodegradable composite stent having core shell structure

Abstract:

Composite textile stents with core-shell structure have been developed. Biodegradable polyvinyl alcohol (PVA) yarns are twisted and then coated with polycaprolactone/polyethylene glycol (PEG) blends. The coated yarns are weft knitted into braids and then thermally treated to form composite stents with core-shell structure. The morphological, mechanical, and biological characteristics of the formed composite stents are evaluated to determine the effects of PEG concentration. Results show that composite stents acquire the flexibility of PVA yarns and elasticity of weft knits. The presence of PEG positively influences composite stent performance. When the PEG concentration is 30 wt%, composite stents exhibit a compressive strength of 6.15 N and cell viability of 97.32% after a 24 h of culture. The selected materials are biodegradable, and the novel structure meets the requirements of bioresorbable vascular stent, which suggests that the proposed composite stents have good potential for advancement.

Biography:

Dr. N Gokarneshan obtained his PhD in Textile Technology from Anna University in 2008. He has a vast academic experience spanning over 30 years and held various positions. His contributions in his field include organizing an international conference, obtaining 3 patents, publishing over 200 articles, presenting papers in many conferences as plenary session, key note and invited speaker. He has contributed many book chapters for edited books published by reputed publishers such as Wiley, Elsevier, Springer Nature, etc. He has authored 20 books including an international monograph. He is recipient of a number of awards and recognitions for noteworthy contributions in his field. He is also a peer reviewer and editorial board member in a number of journals. He has made multidisciplinary contributions in various areas of medicine, engineering, science and technology. He is presently holding position as Professor and Head at the Department of Textile Chemistry at SSM College of Engineering, Komarapalayam, Tamil Nadu, India. His areas of interest include Technical textiles and Nano technology in Textiles.