Introduction: Hypertrophic cardiomyopathy (HCM) is a genetic disease-causing variety of life-threatening complications. Atrial fibrillation (AF) in HCM population constitutes an important step in progression of the disease. Recently developed tool – HCM-AF Risk Calculator v [....] » Read More
Abstract: Medicine changed radically after the plandemic that began in December 2019 and is still ongoing. As we pointed out in an editorial in this outstanding magazine, there is a before and after and that is facilitated by the blindness of 99.9% of doctors in the different [....] » Read More
In this research, we study the fetal heart rate from abdominal signals using multi-fractal spectra and fractal analysis. We use the Abdominal and Direct Fetal Electrocardiogram Database contains multichannel fetal electrocardiogram (FECG) recordings obtained from 5 different wome [....] » Read More
In this study, we explore the possibility that ECG recordings belong to class of multifractal process for which a large number of scaling exponents are required to characterize their scaling structures. We use the BIDMC Congestive Heart Failure database including long term ECG re [....] » Read More
Background: Heart Failure (HF) is a common medical condition and an important public health issue. This carries with it high mortality and frequent hospitalization. There is generally high re-admission rate and patients of heart failure tend to have a duration of stay [....] » Read More
The practice of physical exercises is essential to improve cardiovascular conditioning, as well as clinical improvement of pain, promoting a better quality of life for patients. However, in clinical practice, what is observed is a high incidence of kinesiophobia and a sedentar [....] » Read More
Diabetic cardiomyopathy (DCM) is one of the type 2 diabetes complications, usually accompanied by changes in myocardial structure and function. Nicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in every living cell, is involved in a myriad of metabolic process [....] » Read More
Being the most common metabolic disorder in the world Diabetes Mellitus (DM) can benefit from developing new therapeutic strategies particularly with conventional therapies struggling to properly manage it. Such therapeutic strategies can be made to achieve targeted a [....] » Read More
Background: CABG is most common type of heart surgery. Cardiac Rehabilitation following CABG surgery aims to minimise post- operative pulmonary complications (PPCs) such as atelectasis, arterial hypoxemia, and respiratory infection, decreased exercise tolerance which are the prim [....] » Read More
Adolescence is a very important period of growth and development with major physical, Psychological and metabolic changes occurring in child during which many adult life patterns are formed. Adolescent Prehypertension and hypertension are an important public health issue with an [....] » Read More
Aim of the study: the study aims to clear the initial effect of non-baric oxygen inhalation on the coronary artery spasm. Background: Coronary artery spasm (CAS) is a cardiovascular disorder that plays an important role in the pathogenesis of stable angina, unstable angina, m [....] » Read More
Recurrent pericarditis is one of the most common and notorious complications of acute pericarditis, and if not treated adequately can lead to serious complications such as arrhythmias, constrictive pericarditis, and cardiac tamponade. It affects about 20-30% of the patients diagn [....] » Read More
Diabetic cardiometabolic disorders are characterized by significant changes in cardiac metabolism and are increased in postmenopausal women, which emphasize the role of 17β-estradiol (E2). Despite this, there are few safe and effective pharmacological treatments for these di [....] » Read More
In this paper, we propose a novel approach of Electrocardiogram (ECG) Denoising based on Wavelet/Total Variation (WATV) and Convex fused lasso Denoising with non-convex regularization. This approach consists at first step of applying the Discrete Wavelet Transform (DWT) to the no [....] » Read More
Background: Much concern was directed towards studying cardiovascular dysfunction in patients with multiple sclerosis (MS). However, the mechanisms of such dysfunction are not completely elucidated. Aim of the work: The aim of our work was to assess cardiac and arterial [....] » Read More
Our institution is an adult cardiac surgery department as part of a general hospital. The cardiovascular surgery program began on 2015, since then about 200 – 250 cases per year are performed. Our MICS program initiates on 2019 with 10% of the total cases, 70% on MICS techn [....] » Read More
The rapid success of using human big data has been a novel trend for drug development and discovery. The human genetic techniques including Coding GWAS are generically associated with diseases whereas the expansion of Human Data Ecosystem in multi-geographic regions provide [....] » Read More
Background: Elevated Lp(a) levels are proven as a marker of increased risk of cardiovascular disease. Also,the evidence indicates that patients with psoriasis are at an increased risk of cardiovascular disease.However, as so far, it is not clear whether increased Lp(a) will cause [....] » Read More
Congenital heart disease (CHD) is the most common birth defect and the leading cause of neonate death in China. Clinical diagnosis can be based on the selected 2D key-frames from five views. Limited by the availability of multi-view data, most methods have to rely on the insuffic [....] » Read More
Altered thyroid function is associated with insulin resistance (IR). There are scarce and divergent reports regarding association of thyroid function with insulin resistance in hypertension with or without type 2 DM in African women. The present study aimed at investigating the a [....] » Read More
Heart morphology and function may be non-invasively evaluated by ultrasonography. Rodent models have been used to study several diseases. This study aimed to describe the technique for the evaluation of rats’ heart by ultrasonography. The animals should be anesthetized by a [....] » Read More
Currently, no pharmacological or device-based intervention has been fully validated to reverse the no-reflow phenomenon. Several agents can be used in the case of primary or refractory no-reflow phenomenon, but none of them have a promising effect. We conducted a systematic revie [....] » Read More
Thymolipoma is a rare subtype of benign thymic tumour containing a combination of thymic and adipose tissue. They are often found incidentally or when the tumour causes compression with symptoms varying depending on the location. A 52-year-old female presented to the [....] » Read More
Free wall ruptures occur in 0.01% of the STEMI and NSTEMI populations.They can be repaired by various techniques, depending on anatomical location and tissue quality. A 62-year-old female presented with chest pain and syncopal episodes post alleged assault. Her ECG showed inferio [....] » Read More
Myocarditis has emerged as a serious adverse event after the COVID-19 vaccination. Our review study summarized the findings of Cardiac MRI and clinical follow-up of the patients with COVID-19 vaccine-associated myocarditis. We systematically searched MEDLINE, Embase, and Scopus d [....] » Read More
Stretchable conductive fabric (SCF) is a durable nontoxic textile material coated or blended with conductive metals. Unlike solid metal, SCF effectively conducts electricity with low resistance and maintains conductance when stretched. Thus, it has been hypothesized that SCF elec [....] » Read More
Background. Coronary artery disease is one of the leading causes of death worldwide and the incidence is on the rise in the past decade. One of the main causes is the obesity epidemic and the increase of metabolic syndrome. Hypertension, diabetes, smoking and hyperlipidaemia are [....] » Read More
Introduction: Coronary heart disease and cancer share multiple pathophysiological mechanisms. Studies have shown, many oncologic patients will develop cardiovascular events. However, there is little evidence regarding endothelial dysfunction of patients with oncologic history in [....] » Read More
Introduction: Coronary heart disease and cancer share multiple pathophysiological mechanisms. Studies have shown, many oncologic patients will develop cardiovascular events. However, there is little evidence regarding endothelial dysfunction of patients with oncologic history in [....] » Read More
Background: Brain injury is one of the complications of open heart surgery. Glutamate plays a key role in this process. In this study, we evaluated the neuroprotective effect of memantine as NMDAR inhibitor in patients undergoing on-pump coronary artery bypass graft surgery (CABG [....] » Read More
Introduction: Cardiac diseases and cancers constitute biggest chunk of NCD and can coexist. Hypertension is a common finding in elderly cancer patients, and many patients are either not on medication or not well controlled with medication. Arrythmia, MI are not so uncommon in eld [....] » Read More
Introduction: Coronavirus infection (CI) causes and aggravates various heart rhythm disorders. The aim of our study was to study the course of the most common and potentially dangerous arrhythmia - atrial fibrillation (AF) in patients within 6 months after infection with COVID [....] » Read More
A 63 year-old-man with an adrenal mass and no other medical history presented to the emergency department with central chest pain radiating to neck and 4-5 episodes of vomiting in the last 15 hours. His 12 lead ECG was performed which revealed normal sinus rhythm with ST segment [....] » Read More
Cardiac Amyloidosis is a clinical condition classified in the National Organization of Rare Disorder, estimated that there are 4000 new cases annually in the United States, actual incidence may be higher because of under-diagnosis. Cardiac Amyloidosis is the result of an unstable [....] » Read More
Background: Left bundle branch area pacing (LBBAP) is an emerging physiological pacing modality. LBBAP can preserve intraventricular and interventricular electrical and mechanical synchrony by directly stimulating the cardiac conduction system. However, little attention focused [....] » Read More
Background: Left bundle branch area pacing (LBBAP) is an emerging physiological pacing modality. LBBAP can preserve intraventricular and interventricular electrical and mechanical synchrony by directly stimulating the cardiac conduction system. However, little attention focused o [....] » Read More
Title : Myocardial revascularization and analysis of endpoints in patients with diabetes mellitus in combination with acute and chronic forms of CHD
Mekhman N Mamedov, National Research Center for Preventive Medicine, Russian Federation
The aim of this study was to analyze the features of myocardial revascularization in patients with acute and chronic forms of CHD in combination with diabetes mellitus and to assess complications after a year of observation. Materials and methods. A prospective comparative cli [....] » Read More
Title : Utilizing conditional probability and bayes’ theorem for harmonizing multi-modality cardiac imaging results
Timothy F Christian, Albert Einstein College of Medicine, United States
The use of multiple noninvasive tests in a patient for a specific question in cardiology is becoming more common. While it is expected that each new piece of test information will align, the reality is that each test carries strengths and weaknesses that generate a profile of acc [....] » Read More
Title : Long-term results of concomitant stentless aortic root replacement and reconstruction of the ascending aorta.
John R Doty, Intermountain Medical Center, United States
Purpose. Concomitant ascending aortic aneurysm and aortic valve disease is common in bicuspid aortic valve or in older patients with degenerative valve disease and hypertension. Bioprosthetic aortic root replacement can be combined with a traditional ascending graft for concomita [....] » Read More
Title : 24 hour ambulatory blood pressure profile of hypertensive and pre-hypertesive healthcare workers in a Philippine tertiary hospital
Anna Francesca S Abarquez, Philippine General Hospital, Philippines
Background: Hypertension is a leading cause of cardiovascular morbidity, and its prevalence is increasing most rapidly in developing countries like the Philippines, where there is poor hypertension treatment and control ABPM is an important diagnostic tool among patients because [....] » Read More
Title : Virtual surgery design of double-patch for pulmonary arterioplasty in complete repair of tetralogy of fallot using computational hemodynamics
Yu Pingping, Shanghai Jiao Tong University, China
Objective In tetralogy of Fallot (TOF) with combined pulmonary artery (PA) branch stenosis, proper management of right ventricular outflow tract (RVOT) stenosis is the key to successful surgical correction. The purpose of this study is to evaluate the effective design of double-p [....] » Read More
Title : Computational hemodynamic evaluation for postoperative thrombosis risk based on virtual surgery of systemic-to-pulmonary artery shunt
Jiwen Xiong, Shanghai Jiao Tong University, China
Systemic-to-pulmonary artery shunt is widely used as a palliative operation to treat complex congenital heart disease. Postoperative thrombosis-induced shunt occlusion is a life-threatening complication. Different surgical designs affect the hemodynamic characteristics, which is [....] » Read More
Title : Cardiac vector theory! A paradigm shift in ECG interpretation or a perspective rethinking in ECG translation from scalar to vector form
T Rajini Samuel, Shri Sathya Sai Medical College and Research institute Sri Balaji Vidyapeeth, India
Electrocardiography (ECG) has offered valuable insights in health and disease for nearly a century yet its interpretation remains an arduous task and needs the help of medical experts in that field. Einthoven used the concept of cardiac vector to describe the electrical activity [....] » Read More
Title : A clinical profile of acute coronary syndrome in COVID-19 patients in a provincial town of south India
Shivaling Nisty, Nisty Heart Centre, India
Background: COVID-19 pa,ents are at a higher rick of ACS as associated inflammatory response leads to endothelial damage and plaque rupture. The clinical data of such pa,ents presen,ng with ACS is limited, we did a clinical study of ACS with COVID-19 pa,ents focusing chiefly on c [....] » Read More
Title : Cardioprotective role of empagliflozin in experimentally induced non diabetic different cardiac dysfunction models in rats
Mahmoud Ahmed Khattab, Cairo University, Egypt
Cardiomyopathy specifically affects the structure and function of the heart muscle. It is the leading cause of death.Our aim was to elucidate role and therapeutic mechanisms of empagli?ozin on cardiac dysfunction induced experimentally in non- diabetic rats by three different mod [....] » Read More
Title : The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: Prospective cohort study: Results from the (ECASIS) study
Mohamed Nabil Elshafei, Hamad General Hospital, Qatar
Background and purpose: Uncertainty remains regarding the impact of enteric-coated aspirin (EC-ASA) on secondary prevention of ischemic stroke compared to plain aspirin (P-ASA). Hence, this study was designed to investigate the efect of EC formulation on ASA response via eva [....] » Read More
Title : Computational hemodynamic study of systemic-to-pulmonary arterial shunt with different design of conduit position.
Jinlong Liu , Shanghai Jiao Tong University, China
Object: Different types of systemic-to-pulmonary arterial shunts are used as the palliative treatment for the first-staged procedure of congenital heart disease (CHD). Although the surgical techniques improved over the years, the position of the conduit implanted between the syst [....] » Read More
Title : Triglyceride-glucose index for predicting repeat revascularization and instent restenosis in patients with chronic coronary syndrome undergoing percutaneous coronary intervention
Xuantong Guo, Chinese Academy of Medical Sciences, China
Background: The triglyceride-glucose (TyG) index, a reliable surrogate indicator of insulin resistance, is demonstrated independently associated with coronary artery disease of various clinical manifestations. This study aimed to investigate the prognostic value of the TyG index [....] » Read More
Title : Comparison of clinical and angiographic profiles of patients with or without left main coronary artery disease
Suman Kumar Biswas, Directorate General of Health Services (DGHS), Bangladesh
Background: Left main coronary artery (LMCA) disease constitutes the highest risk lesion subset of coronary artery disease (CAD) population. Flow dynamics and pathophysiology in left main coronary artery are different from that of other coronaries. So traditional risk factors mig [....] » Read More
Title : Prevalence of microvascular dysfunction in patients with heart failure with preserved ejection fraction : Angiographic pararmeters
Tamer Moustafa, Zagazig University, Egypt
Objective: To study, using validated angiography indices, coronary blood flow and myocardial perfusion of the microcirculation to assess whether there is greater Microvascular Disease (MVD) in patients with microvascular angina and HFpEF compared to those who do not have. Pati [....] » Read More
Title : Decoding the genomics of abdominal aortic aneurysm reveals links to lipid metabolism and immune response
Cuiping Pan, Greater Bay Area Institute of Precision Medicine, Fudan Univ., China
Abdominal aortic aneurysm (AAA) is a large vessel cardiovascular disease that ranks the 10th cause-of-death in developed countries. Early screening has proven to significantly reduce its risk of rupture, therefore identifying individuals with higher risk will contribute to improv [....] » Read More
Title : Cardioprotective effect of c-kitve amniotic fluid mesenchymal stem cells in in-vitro model of myocardial ischemia reperfusion injury
Manali Jain, Sanjaya Gandhi Graduate Institute of Medical Sciences, India
Myocardial ischemia-reperfusion injury (MIRI) is the main pathological manifestation of heart failure. Recently, c-kitve amniotic fluid mesenchymal stem cells (c-Kit+ve AF-MSC) have been shown to have cardiomyogenic potential under in vitro conditions. While the c-Kit+ve AF-MSC d [....] » Read More
Title : Cardiometry: A new fundamental scientific field in cardiology
Mikhail Rudenko, Russian New University, Russian Federation
Listeners will learn about a fundamental discovery of a new blood flow mode with low friction due to structuring the flow in each cardiac cycle in the form of alternating rings of blood cells and plasma, which is accurately described mathematically by the authors. This radically [....] » Read More
Title : The cause of transient ischemic attacks
Ermoshkin Vladimir Ivanovich, Russian New University, Russian Federation
Transient ischemic attacks (TIA) accounts for about 80% of all strokes. TIA occurs when microvessels and capillaries in some part of the brain become clogged as a result of one of two mechanisms - either thrombosis or embolism. But where do these obstacles to blood flow disappear [....] » Read More
Title : ECG in athletes: Limits of normal
Samir Morcos Rafla, Alexandria University, Egypt
Classification of abnormalities of the athlete's ECG Group 1: common and training-related ECG changes: Sinus bradycardia, First-degree AV block, Incomplete RBBB, Early repolarization, Isolated QRS voltage criteria for LV hypertrophy. Group 2: uncommon and training-unrel [....] » Read More
Title : Dynamics of myocardial deformation properties of left ventricle after revascularization in patients of chronic coronary artery disease with preserved ejection fraction
Shukhrat Doniyorov, Republican Specialized Scientific and Practical Medical Center of Cardiology, Uzbekistan
Aim: The purpose of the research was to evaluate the property of left ventricular myocardial deformation in patients with chronic coronary artery disease (CAD). Methods: 136 patients were selected with chronic coronary artery disease aged between 38 and 74 years. All par [....] » Read More
Title : Microbiome, its associated bacterial metabolites and inflammatory, profile of a heart failure cohort
Adilah Ahmad, University of Western Australia, Australia
Heart failure is the end stage of most cardiovascular diseases and remains a significant health problem in Australia and globally. The objective of this study was to assess whether heart failure (HF) patients with LVEF ≤45% had an altered gut microbiome and associated metaboli [....] » Read More