Herbal medicines have been used continuously and most frequently throughout history. Numerous human ailments have traditionally been treated by herbal treatments under every condition. Nowadays, we have the option to use them instead of synthetic drugs because they have fewer side effects. Throughout the past century, numerous plant extracts have been the focus of pharmacological and chemical studies to better understand their chemical properties and possible uses in traditional medicine. Due to the high risk of cardiovascular problems such as congestive heart failure, irregular heartbeat, renal failure, and coronary heart disease may shorten life expectancy and increase morbidity. Healthy lifestyles and dietary naturally occurring bioactive substances are thought to protect against coronary artery disorders. Consuming plant-food bioactive derivatives, such as polyphenolic chemicals, peptides, oligosaccharides, vitamins, and unsaturated fatty acids, has been shown to have preventive benefits against cardiovascular disorders in pre-clinical and clinical research. Several dietary components may support human cardiovascular health as has been identified in recent years. Fruits, vegetables, cereals, and other dietary plants contain more than 5,000 unique phytochemicals including vitamins C and E, flavonoids, flavanols, catechins, anthocyanins, polyphenols, tannins, polysaccharides, fibre, saponins, sterols, as well as minerals like K, Ca, and P are some of their primary bioactive components which are used for the treatment of heart-related diseases. The current manuscript outlines bioactive components that lower blood pressure, including their physiological mechanisms, particularly emphasizing ACE inhibitors.