Oxygen reversal of coronary artery spasm with modification of international standards for the diagnostic criteria of coronary vasomotor disorders (Yasser's modification or oxygen test) retrospective observational study; 17-case reports

Title : Oxygen reversal of coronary artery spasm with modification of international standards for the diagnostic criteria of coronary vasomotor disorders (Yasser's modification or oxygen test) retrospective observational study; 17-case reports

Abstract:

Aim of the study: the study aims to clear the initial effect of non-baric oxygen inhalation on the coronary artery spasm.

Background: Coronary artery spasm (CAS) is a cardiovascular disorder that plays an important role in the pathogenesis of stable angina, unstable angina, myocardial infarction, and sudden cardiac death. Nitrate, calcium channel blockers, and statins are known established medications in the reversal of coronary artery spasms. Oxygen safety versus adverse effects of nitrate, calcium channel blockers, and statins are comparable.

Method of study and patients: My case study was an observational-retrospective seventeen case report series. The study was conducted in Fraskour Central Hospital, Kafr El-Bateekh Central Hospital, and physician outpatient. The author reported seventeen cases of acute angina with rest chest pain over about 38 months; starting on December 15, 2018, ended on February 7, 2022.

Results: The mean age is 43.2 with the female sex predominance (64.71%). Housewives (29.41%) and students (23.53%) are the most affected occupations. The main complaint is chest pain (64.71%). The most common associated risk factors are female sex (64.71%) and stress (23.53%). Drug-induced (23.53%); hyperventilation syndrome-induced (23.53%); and CO toxicity-induced coronary artery spasm (17.65%) are common diagnoses. The dose of inhaled O2 dose that achieved the reversal of CAS varied from 5 to 12 liter. A maximal dose (12 minutes) was given for CO toxicity. The duration of inhaled O2 dose that achieved the reversal CAS varied from 15 to 80 minutes. Maximal duration (80 minutes) was given in CO toxicity. The complete response had happened in 94.12%.

Conclusion: Dramatic clinical reliving and reversal response of electrocardiographic ST-segment depression after oxygen inhalation is an indication of its initial use in coronary artery spasms. Yasser’s Modification or Oxygen test for the past “international standards for the diagnostic criteria of coronary vasomotor disorders” improves patient safety and decreases the hazards of nitrate and other medications.

Keywords: Coronary artery spasm; Ischemic heart disease; Oxygen; International standards for the diagnostic criteria of coronary vasomotor disorders; Yasser’s modification; Oxygen test

Audience Takeaway

• Yasser’s Modification or oxygen test enables the clinician to test the presence of coronary artery spasm
• This test or modification is easy, safe, cheap, and available
• Widening this research to expand their research or teaching is advisable
• The modification already provides a practical solution for starting with oxygen in coronary artery spasms before drugs
• I think that the test will be effective if co-associated  and is studied with coronary angiography
• Avoidance of nitrates, calcium antagonists, and statins side effects is the main target

Biography:

Dr. Yasser Mohammed Hassanain Elsayed is a distinguished scientist, critical care physician, and cardiologist affiliated with the Egyptian Ministry of Health. With an impressive publication record of 123 articles, he has contributed significantly to the scientific community. Notably, he has introduced innovative concepts such as the Wavy Triple Electrocardiographic Sign (Yasser’s Sign) associated with hypocalcemia and the Graded Phenomenon (Yasser’s Phenomenon). His research extends to various electrocardiographic signs, including the Connected Aircraft Squadron Electrocardiographic Sign and the Electrocardiographic Passing Phenomenon (Yasser’s Phenomenon or Flying Phenomenon). Dr. Elsayed has also delved into the realm of COVID-19, publishing 37 articles related to the pandemic. Beyond his research, he is an accomplished speaker at 20 international conferences, a diligent reviewer of 210 articles, and an editor for 187 journals. His expertise is further highlighted by his role as an OCM for seven international conferences and as an instructor for seven official and 77 non-official programs. Noteworthy are his proposed maneuvers and modifications, such as Yasser’s Maneuver for Regaining Consciousness in Psychogenic Coma and Yasser’s Modification for Oxygen Testing in Coronary Artery Spasms. Dr. Elsayed's Three and One Method (Yasser’s Method) addresses hypotension induced by Streptokinase in Acute Myocardial Infarction. His groundbreaking work has garnered him nominations for prestigious awards, including the Breakthrough Prize and Einstein Prize, and he holds an impressive 98 excellence certificates.