Pulmonary heart disease, also known as cor pulmonale, is a condition characterized by the enlargement and dysfunction of the right side of the heart. This condition is typically a consequence of prolonged high blood pressure in the pulmonary arteries, which are responsible for carrying blood from the heart to the lungs. Chronic respiratory conditions such as chronic obstructive pulmonary disease (COPD), pulmonary hypertension, and interstitial lung diseases are common contributors to the development of pulmonary heart disease. The increased resistance in the pulmonary circulation forces the right side of the heart to pump harder, leading to its enlargement and potential failure over time. Indications may involve difficulty breathing, tiredness, and edema in the legs. Timely diagnosis and management of the underlying respiratory condition are crucial in addressing and preventing the progression of pulmonary heart disease.