Cardiovascular pharmacology and therapeutics form the backbone of managing heart-related conditions through targeted drug development and clinical applications. Medications like beta-blockers, ACE inhibitors, and antiplatelet agents play a critical role in treating hypertension, heart failure, and coronary artery disease. Advances in this field have led to novel therapeutics, including sodium-glucose cotransporter-2 (SGLT2) inhibitors and PCSK9 inhibitors, which offer new hope for patients with complex cardiovascular conditions. Ongoing research focuses on personalized medicine, exploring how genetic factors influence drug response to optimize treatment strategies. By blending pharmacology with innovative therapies, this field aims to improve cardiovascular outcomes while minimizing side effects.