Cardiac cachexia is a complex and severe condition characterized by the unintended loss of weight, muscle atrophy, and weakness in individuals with chronic heart failure. This condition goes beyond mere weight loss, encompassing a profound depletion of lean body mass and fat stores. It poses a significant challenge in the management of heart failure, often leading to increased morbidity and mortality. The underlying mechanisms of cardiac cachexia involve a complex interplay of inflammation, hormonal imbalance, and metabolic disturbances. Clinically, patients with cardiac cachexia experience a decline in functional capacity and a compromised quality of life. Management strategies typically involve a multidisciplinary approach, focusing on nutritional support, exercise rehabilitation, and addressing the underlying causes of heart failure. Research into the pathophysiology and treatment options for cardiac cachexia is ongoing, aiming to enhance our understanding and improve the prognosis for individuals affected by this debilitating condition.
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