Atherosclerosis is a complex and progressive cardiovascular condition that involves the gradual buildup of plaque in the arteries, restricting blood flow and potentially leading to serious health complications. This condition stems from the accumulation of cholesterol, fats, and inflammatory cells on the inner walls of arteries, forming atherosclerotic plaques. As these plaques grow, they can narrow the arteries, impeding the smooth flow of blood to vital organs and tissues. Atherosclerosis is a significant contributor to various cardiovascular diseases, including heart attacks, strokes, and peripheral artery disease. Risk factors for developing atherosclerosis include high cholesterol levels, hypertension, smoking, diabetes, and a sedentary lifestyle. Understanding the underlying mechanisms of atherosclerosis is crucial for developing effective prevention and treatment strategies. Lifestyle modifications, such as adopting a heart-healthy diet, regular exercise, and managing risk factors, play a pivotal role in mitigating the progression of atherosclerosis and promoting overall cardiovascular health. Ongoing research continues to unravel the intricacies of atherosclerosis, paving the way for innovative therapies and interventions aimed at reducing its impact on global health