Cardiomyocytes, often referred to as cardiac muscle cells, are the specialized cells responsible for the contraction of the heart. These cells form the muscular tissue of the myocardium, the middle layer of the heart wall. Cardiomyocytes are essential for maintaining the rhythmic pumping action of the heart, which propels blood throughout the circulatory system. Unlike skeletal muscle cells, cardiomyocytes are characterized by their branching structure and intercalated discs, which facilitate coordinated contractions. The unique feature of automaticity, allowing cardiomyocytes to generate electrical impulses independently, contributes to the heart's intrinsic ability to initiate and regulate its own beating. Given their crucial role in cardiac function, understanding the physiology and behavior of cardiomyocytes is vital for unraveling the complexities of heart health and developing therapeutic interventions for cardiovascular diseases.