Title : Enhancing surgical outcomes in infants with ductal-dependent pulmonary blood flow
Abstract:
Infants with ductal-dependent pulmonary blood flow conditions pose unique challenges in surgical management. This study aims to investigate personalized treatment modalities, including computer-aided anatomical modeling and hemodynamic analysis, to optimize surgical planning and predict postoperative outcomes. The primary objective is to assess the impact of personalized treatment approaches on surgical outcomes for these infants, particularly evaluating the efficacy of stent insertion or shunt deployment. We employ computational fluid dynamics (CFD) modeling and digital twin simulations, analyzing seven preoperative patient datasets for parameters like wall shear stress and velocity profiles across stented and shunted configurations. Results reveal differences in velocity profiles, with stent models showing lower velocities. Wall shear stress analysis favors PDA stent insertion over shunts, while pressure drop varies across configurations. These findings underscore the potential of PDA stent insertion in mitigating hemodynamic complications and improving surgical outcomes, highlighting the importance of tailored approaches. In conclusion, this study emphasizes the promising role of stenting in enhancing flow dynamics for infants with ductal-dependent pulmonary blood flow conditions, indicating the need for further investigation into personalized treatment modalities' efficacy in pediatric cardiac interventions.
Audience Take Away
The audience will gain insights into personalized treatment modalities for infants with ductal-dependent pulmonary blood flow conditions, particularly regarding the efficacy of stent insertion or shunt deployment. This knowledge can be directly applied in clinical settings to optimize surgical planning and predict postoperative outcomes for better patient care.
