PFO closure in thrombophilia: Evaluating the evidence for patients without prior thromboembolic events

Title : PFO closure in thrombophilia: Evaluating the evidence for patients without prior thromboembolic events

Abstract:

Patent Foramen Ovale (PFO) is a common anatomical lesion occurring in 20-34% of the population, and it may be a cause for paradoxical embolism to the cerebral or coronary arteries causing stroke or myocardial ischemia. PFO management in patients with thrombophilia without prior cerebrovascular events remains poorly defined due to lack of robust data. This study aimed to review the existing literature on PFO closure in such patients, identifying a significant gap in the relevant research. The absence of targeted research highlights the challenge of formulating clear guidelines for this high-risk group. Our findings emphasize the need for large-scale, well-designed studies to better inform treatment strategies for thrombophilia patients with PFO, aiming to enhance clinical decision-making and patient care.

Biography:

Mr Nikolaos Ziogas is a 6th-year Medical Student currently enrolled in the Medical School of European University Cyprus in Nicosia, where he has been studying since September 2019. His internship experiences include serving as an observer at Hammersmith Hospital of Imperial College Healthcare NHS Trust in the Cardiology Department in London from June to July 2023. Since January 2023, he has been working as a trainee at Apollonion Private Hospital in Nicosia. His extracurricular activities include serving as a peer teaching assistant from 2023 to 2025. He is also the Vice Writers’ Director of the peer-reviewed journal "Edge of Medicine."