Agustin Joison, Cordoba Catholic University, Argentina
Introduction: Globally, ischemic heart disease has become one of the leading causes of disability-adjusted life years (DALYs), ranking first among adults over the age of 50. Residual risk can be classified into three main domains, residual lipid risk: persists despite LDL-C contr [....] » Read More
Title : Revolutionizing heart health through Personalized & Precision Medicine (PPM): Towards personalized cardiovascular prevention, precision cardiac care & rehabilitation via optimizing Cardiac Hospital Networks
Sergey Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Understanding personalized & precision cardiology (PPC) focuses on customizing medical interventions based on an individual’s unique genetic profile, biomarkers, targets and personal health data. Unlike conventional cardiology, which relies on generalized treatment guid [....] » Read More
Title : Antibody-proteases as unique biomarkers, potential targets and translational tools of the next step generation to be used in personalized and precision cardiology practice
Sergey Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Catalytic Abs (catAbs) are multivalent immunoglobulins (Igs) with a capacity to hydrolyze the antigenic (Ag) substrate. In this sense, proteolytic Abs (Ab-proteases) represent Abs to provide proteolytic effects. Abs against Cardiac Myosin (CM) with proteolytic activity exhibiting [....] » Read More
Title : Investigation of bergapten’s pharmacological activity against doxorubicin induced cardiotoxicity: supporting evidence from cellular and animal models
Bijoy Krishna Banik, National Institute of Pharmaceutical Education and Research (NIPER)-Guwahati, India
Introduction: Doxorubicin (DOX) is a broadly used anthracycline anticancer drug, but its therapeutic application is limited by cumulative, dose?dependent cardiotoxicity that may culminate in heart failure. Oxidative stress, mitochondrial impairment and activation of apoptotic pat [....] » Read More