Title : Dynamics of myocardial deformation properties of left ventricle after revascularization in patients of chronic coronary artery disease with preserved ejection fraction
Abstract:
Aim: The purpose of the research was to evaluate the property of left ventricular myocardial deformation in patients with chronic coronary artery disease (CAD).
Methods: 136 patients were selected with chronic coronary artery disease aged between 38 and 74 years. All participants underwent the following examinations and diagnostic tests: evaluation of risk factors, physical examination, laboratory blood tests, 12-lead ECG, 24-ABPM, TTE, two-dimensional speckle tracking echocardiography(STE), coronary angiography(CAG).
Global Longitudinal Strain (GLS) was assessed within 48 hours and 30 days after percutaneous coronary intervention (PCI). The total number of candidates were divided into 2 groups. The first group with single-vessel CAD, with the average GLS -17,76±0.59%. The second group of patients consisted of two-vessel CAD, with GLS around -15,77±0.57%.
Results: In the first category of patients who underwent revascularization with PCI, the values of GLS within 48 hours and in 30 days were -17,81±0.69 and -18,12±0.63 respectively (P>0.05 and P=0.015). The second group had GLS -15.76±0,63 and -16,13±0.71 (P>0.05 and P=0.024), in the same specific periods.
Conclusion: The research findings indicate that after PCI, there is a significant increase of GLS index in patients with chronic coronary artery disease in 30 days.
Audience Takeaway:
The audience will be able to Implement non-invasive method of diagnostics of coronary atherosclerosis. The prediction of severity of coronary atherosclerosis in patients with coronary artery disease by using speckle tracking echocardiography. It provides practical solution to diagnosing of coronary artery disease prior to percutaneous coronary intervention especially by using global longitudinal strain(GLS). GLS can be utilized to detect hibernating myocardium so it has huge potential for expanding research.
