Keliang Xie

Biography:

Professor Keliang Xie is a leading clinician-scientist in the Department of Critical Care Medicine and Anesthesiology at Tianjin Medical University General Hospital, China. His research focuses on the therapeutic potential of molecular hydrogen in critical illness, with particular emphasis on sepsis, multiple organ dysfunction, and perioperative neuroprotection. Through extensive experimental studies, he has demonstrated that hydrogen inhalation improves survival, mitigates systemic inflammation, and preserves mitochondrial function in sepsis models. His work has also revealed novel mechanisms, including activation of the Nrf2/HO-1 pathway, regulation of mitochondrial dynamics, and suppression of innate immune signaling. Translating laboratory findings into practice, he conducted pioneering clinical studies showing that hydrogen inhalation reduces postoperative delirium and improves physiological outcomes in surgical patients. Author of numerous high-impact publications and reviews, Professor Xie has significantly advanced the field of hydrogen medicine, establishing molecular hydrogen as a promising adjunctive therapy in critical care and anesthesiology.