Title : The exploration of lived experiences and the associated relationship with physical activity and exercise for individuals with ANOCA
Abstract:
Background: Angina with No Obstructive Coronary Artery disease (ANOCA) is an umbrella term encompassing multiple underlying pathologies. Unlike traditional coronary artery disease (CAD), it is a complex condition, stemming from multifactorial structural and functional abnormalities within the coronary vasculature. There is a paucity of research exploring the lived experiences of those with ANOCA and the associated relationship with physical activity and exercise.
Aim: To investigate the lived experiences of individuals with ANOCA and the associated relationship with physical activity and exercise.
Methods: Semi-structured, online, individual phenomenological interviews were conducted with ANOCA patients, focusing on their lived experiences and subsequent relationship with physical activity and exercise. Prior Public Involvement in Research (PiR) work was completed to develop one-to-one interviews, aligning research with patient priorities. An inductive, approach was employed to capture the detailed narratives of the functional impact of ANOCA on patients’ lives. Reflexive Thematic Analysis will be conducted to identity and explore themes. Findings will be validated via member checking and triangulation of data to enhance analytical rigour. Inclusion criteria were specified as adults (≥18 years), who had medically confirmed diagnosis under the umbrella term of ANOCA.
Results: 25 participants completed 1:1 interviews (M=3; 54.7 ± 4 years, F=22; 58.1 ± 8.6 years) from the UK, USA, Canada, Australia and Belgium. Initial findings suggest that patients self-report high fitness levels, holding very active lifestyles at the onset of condition symptoms. Patients report exertional symptoms triggered at specific heart rates, ranging from 100 to 140 bpm, which limits their exercise capacity and prevents the continuation of physical activity and exercise. Patients self-report clinical dismissal due to a perceived lack of provider knowledge, awareness and empathy regarding ANOCA. Patients report heightened anxiety and diminished trust in healthcare systems and medical personnel. Further analysis is planned.
Conclusion: This research may provide valuable insight into the relationship of those with ANOCA and physical activity, increase awareness of ANOCA, and support clinical decision making. This research will look to inform the co-design of physical activity and exercise programmes for ANOCA patients, considering symptom triggers, manageability and accessibility.


