Title : A study of clinical profile of raised NT-proBNP in elderly patients with good LV systolic function
Abstract:
Introduction: NT-proBNP (N-terminal pro-B-type Natriuretic Peptide) is a blood test used mainly to diagnose and monitor heart failure. It measures a hormone released by the heart when the heart muscle is stretched due to increased pressure or fluid overload.
Methodology: The aim of this study was mostly to assess the profile of 25 elderly patients with raised NT pro BNP in elderly patients with good LV systolic function at our centre located in Kalaburagi, India and also studied in details with the various associations.
Results: Out of 25 participants, 15 patients (60%) were females and 10 patients (40%) were males. The mean age was 69.68 ± 9.70 years and ranging from 60–95 years. All participants presented with shortness of breath and 1 patient (4%) had cough. Hypertension was present in 7 patients (28%), diabetes mellitus in 6 patients (24%), coronary artery disease in 2 patients (8%), chronic kidney disease in 1 patient (4%) and 2 patients has malignancy (8%). Left ventricular hypertrophy was observed in 4 patients (16%), trivial mitral regurgitation in 2 patients (8%), and tricuspid regurgitation in 1 patient (4%). The mean NT-proBNP level among participants was 2384.84 ± 2707.67 pg/mL
Conclusion: NT-proBNP is excellent diagnostic tool to diagnose the heart failure, its severity and also monitor the treatment especially in elderly individuals with good LV systolic function. It’s a must in evaluation of shortness of breath. It detects diastolic dysfunction effectively especially in elderly patients.
