Between 1970 and 1980 there were experiences and series of patients operated on Direct Coronary Surgery without the use of extracorporeal circulation. During the 80 and 90 the Technique was developed. The MIDCAB was the one that promoted the development of Coronary Surgery withou [....] » Read More
The aim of the study: was to analyze the characteristics of risk factors (RF) for cardiovascular disease (CVD) in individuals with type 1 diabetes mellitus. Materials and Methods: This cross-sectional multicenter study included 453 male and female patients with a verified [....] » Read More
Pulmonary Arterial Hypertension (PAH) is still a devastating illness with substantial morbidity and death outcomes. Taking into account that the disease advances quickly for many patients, and is commonly associated with severe clinical symptoms, new treatment options are still r [....] » Read More
Torsades de Pointe (TdP) is a fatal arrhythmia that is a potential sequela of a prolonged QT interval. Most cases of TdP arise from medication-induced or congenital prolonged QT1. This case highlights an underrecognized association between panhypopituitarism and TdP, demonstrat [....] » Read More
Background: Anomalous aortic origin of a coronary artery (AAOCA) is a rare congenital anomaly associated with myocardial ischemia and sudden cardiac death. The risk is particularly significant when the left main coronary artery (LMCA) arises from the right coronary sinus and [....] » Read More
Heart failure remains a major complication following myocardial infarction (MI), driven in part by sterile inflammation and adverse ventricular remodeling. While sodium-glucose cotransporter-2 (SGLT2) inhibitors have demonstrated robust cardiovascular benefits independent of glyc [....] » Read More
A 64-year-old woman with a history of diverticulosis and duodenal ulcer presented with classic signs and symptoms of ST-elevation myocardial infarction (STEMI), including chest pain typical of cardiac origin, ST elevations on ECG, and raised cardiac biomarkers. She was a former s [....] » Read More
Background: Gender differences in cardiac structure may reflect body size and comorbidity patterns and have implications for diagnosis and risk stratification in older adults. The aim is to compare left ventricular wall thickness (LVWT) and left atrial (LA) size between older men [....] » Read More
Background: Gender differences in cardiac structure may reflect body size and comorbidity patterns and have implications for diagnosis and risk stratification in older adults. The aim is to compare left ventricular wall thickness (LVWT) and left atrial (LA) size between older men [....] » Read More
Introduction: The fibrinolytic activity in human plasma was subsequently shown to depend on activation of a plasminogen as precursor. As plasmin derives from plasminogen, it is possible that microplasmin also has a precursor, microplasminogen. The present study describes the &nbs [....] » Read More
The LKB1–AMPK signaling pathway is a core regulatory axis of cellular energy homeostasis and a pivotal hub in stress adaptation. As an evolutionarily conserved metabolic sensor, this pathway coordinately regulates glucose, lipid, and protein metabolism, thereby maintaining [....] » Read More
Introduction: Mobile ECG applications detect the heart's electrical signals from the skin surface using the electrodes and sensors. The signals are amplified and then filtered to remove artifacts. The software identifies the various components of the ECG waves, analyze t [....] » Read More
Cardiovascular diseases (CVDs) remain a leading cause of global morbidity and mortality, necessitating the exploration of complementary and integrative therapeutic strategies alongside conventional pharmacotherapy. Herbal medicines and natural products have long been utilized for [....] » Read More
The prevalence of cardiovascular diseases (CVDs) has significantly increased in recent years due to environmental changes, heavy diets, and lifestyle modifications. As a result, the term "hridroga," which refers to heart-related conditions in Ayurveda, has grown in popu [....] » Read More
In vascular medicine, the greatest challenge is not the complexity of the disease, but the silence with which it evolves. We must now harness predictive intelligence to break that silence. This presentation posits that the potential of vascular medicine lies in the seamless in [....] » Read More
In cardiovascular therapeutics, procedures such as heart transplants and coronary artery bypass graft are pivotal. However, an acute shortage of organ donors increases waiting times of patients, which is reflected in negative effects on the outcome for the patient. Post-procedura [....] » Read More
Genetic heart diseases are common causes of sudden cardiac death (SCD) in the young and are typically divided into inherited cardiomyopathies and primary electrical heart diseases. Cardiomyopathies associated with the risk of SCD include hypertrophic cardiomyopathy (HCM) and arrh [....] » Read More
Rationale: Atrial fibrillation (AF) is the most common arrhythmia. It is known leading cause of ischemic cerebrovascular accidents. Yasser’s fibrillation (sinusoidal AF) or mixed AF is a new cardiovascular discovery. The partial sino-atrial nodal function has an essential r [....] » Read More
A decrease in erythrocyte electrophoretic mobility serves as an important diagnostic marker of pathological conditions associated with impaired gas exchange, microcirculation, and tissue trophism, often leading to systemic hypoxia and deterioration of the patient's clinical s [....] » Read More
Background: Liver cirrhosis is associated with characteristic Electrocardiographic (ECG) and cardiac structural abnormalities, including QTc prolongation and low voltage. In those with heart disease, these changes are often encompassed under the entity of cirrhotic cardiomyopathy [....] » Read More
Background: The atherogenic index of plasma (AIP), derived from the triglycerides/high-density lipoprotein cholesterol ratio, reflects the balance between atherogenic and protective lipoproteins. Although it has been associated with cardiovascular risk factors, such as obesity, a [....] » Read More
This keynote highlights how movement as medicine supports the goals of the Cardiology World Conference 2026 by emphasizing innovative, preventive approaches to heart health. For cardiologists, cardiovascular surgeons, researchers, healthcare practitioners, academicians, industry [....] » Read More
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. The primary prevention of CVD is dependent upon the ability to identify high-risk individuals long before the development of overt events. This highlights the need for accurate risk stratificatio [....] » Read More
Nanomedicine, or the use of materials with at least one dimension less than 100 nm, has led to improved disease prevention, diagnosis, and treatment. This talk will cover recent advances in the use of nanomaterials to prevent, diagnose, and treat cardiovascular diseases. Specific [....] » Read More
Aortic stenosis (AS) is a common and progressive valvular heart disease, particularly in older adults, yet diagnosis and longitudinal monitoring remain highly dependent on access to echocardiography and expert interpretation. Scalable, noninvasive tools that can identify AS and [....] » Read More
Background: Heart transplantation remains the definitive therapy for end-stage heart failure, but allograft rejection continues to be a major cause of morbidity and graft dysfunction. Traditional surveillance has relied on endomyocardial biopsy (EMB), which provides direct histol [....] » Read More
Introduction: Central artery elasticity is a measure of the artery’s response to the impulse of blood expelled from the left ventricle. The Doppler ultrasound measurement of central artery flow velocity, and its variation over a cardiac cycle, provides a measure of the arte [....] » Read More
Cardiovascular disease accounts for approximately 18 million deaths annually, yet up to 80% of premature cardiac events are preventable, and medication adherence in chronic cardiovascular conditions remains at just 50–60%. This gap is not a knowledge deficit; it is a behavi [....] » Read More
Background. A team of international cardiologists has suggested replacing the complex experimental “Randomized Controlled Trials (RCTs)” with simpler concepts named “Joint Option”. The idea is perfect, but the solution is rather difficult. Experiments over [....] » Read More
Cardiovascular disease and tropical infections constitute a major and increasingly interconnected dual burden in underserved regions, particularly within low- and middle-income countries where healthcare systems remain fragmented and resource-constrained. This poster proposes a s [....] » Read More
Introduction: Modern cardiovascular care is rapidly evolving toward integrated, multidisciplinary management supported by advanced diagnostic and monitoring technologies. The “Heart Team” model, endorsed by the European Society of Cardiology, promotes collaborati [....] » Read More
Chronic pain is associated with the leading cause of disability in the world, just as cardiovascular diseases represent the highest incidence of death in the world. Both pathologies generate a high demand for health services and represent a high global population risk. In [....] » Read More
Relevance: Obesity is a leading modifiable risk factor for cardiovascular diseases (CVD). Despite the recognized role of physical activity (PA) in the treatment of obesity, existing recommendations are general in nature, which reduces their effectiveness and safety. Determin [....] » Read More
Introduction: Quadricuspid aortic valve (QAV) is an exceedingly rare congenital cardiac malformation, with an estimated incidence of 0.008% to 0.043%. It is primarily characterized by the presence of four functional cusps, which often leads to progressive aortic regurgitation (AR [....] » Read More
Herbs have long served as foundational sources of medicinal agents and continue to play a pivotal role in both traditional and modern pharmaceutical practices. Among these, several naturally derived compounds exhibit promising therapeutic potential against cardiovascular diseases [....] » Read More
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Introduction: A concerning increase in coronary artery disease (CAD) among younger Indians calls attention to genetic biomarkers that indicate early vascular stress. The tumor suppressor gene p53, known primarily for its oncogenic role, also modulates vascular apoptosis and infla [....] » Read More
Background: Cardiovascular diseases (CVDs) are major health problem throughout the world and common cause of premature morbidity and mortality. Today CVD accounts for approximately 30% deaths worldwide including nearly 40% in high income countries and about 28% in middle and low [....] » Read More
Contemporary cardiac disease modeling and electrocardiographic interpretation remain largely dominated by waveform-centric heuristics, statistical signal processing, and black-box artificial intelligence. Although such methods may provide empirical classification, they often fail [....] » Read More
Statement of the Problem: Air pollutants can affect the human cardiovascular system, but their impact on cardiac conduction remains unclear. We have undertaken a systematic review to compile the existing evidence Methodology & Theoretical Orientation: We conducted a compre [....] » Read More
Title : Fats of life, the skinny on novel lipid therapies beyond statins
Ahdy Wadie Helmy, Indiana University School of Medicine, United States
With Cardiovascular disease still the primary killer of adults globally, tackling lipid disorders has proven extremely useful from the statins experience since the early nineties. However, goals are not met regarding the lipid parameters for the vast majority of the world adult p [....] » Read More
Title : Beyond PCSK9: The next wave of lipid-lowering and thrombosis prevention - from bench to breakthrough
Narendra Kumar, HeartbeatsZ Academy, United Kingdom
In 2015, we celebrated PCSK9 inhibitors. In 2026, we're potentially approving FOUR revolutionary drug classes simultaneously. But will they succeed where others failed?" First, we examine Factor XI/XIa inhibition as a strategy to uncouple thrombosis from haemostasis, [....] » Read More
Title : Personalized and Precision Medicine (PPM) and PPN-guided cardiology practice as a unique model via translational applications and upgraded business modeling to secure human healthcare, wellness and biosafety
Sergey Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, Personalized and Precision Medicine (PPM). The pace of inno-vation in Personalized & Precision Cardiology (PPC) is thus becoming fast including: The success [....] » Read More
Title : circHIPK3 regulates nucleolin phase separation in aging: Insights from AI-driven predictionandexperimental validation
Yangxin Li, Soochow University, China
Cardiac aging is closely linked to cardiomyocyte (CM) senescence. Ribosome biogenesis plays acritical role in triggering CM cell cycle reentry; however, the specific activators and upstreamregulatorsofthis process remain unclear. Circular RNAs (circRNAs) have emerged as key regul [....] » Read More
Title : Current approaches to anti-angina drug treatment in Chronic-stable Angina Pectoris (CSAP) in US primary care and cardiology – A cross-sectional, blinded standard-of-care survey
Uwe Peter Tigor, Auxilius Pharma, United States
Background: Availability and use recommendations of anti-anginals in chronic-stable angina pectoris (CSAP) has changed little since the last anti-anginal was FDA approved in 2006. Recent large outcomes studies have changed consensus on management of CSAP. Guidelines again focus o [....] » Read More
Title : Cocaine induced Accelerated Idioventricular Rhythm (AIVR)
Faizan Butt, Rutgers Jersey City Medical Center, United States
Introduction: Cocaine-induced cardiotoxicity is a well-recognized phenomenon associated with a broad spectrum of cardiovascular complications, including arrhythmias. We present a case of a 26-year-old male with a history of mitral valve prolapse (MVP) who developed accelerat [....] » Read More
Title : The exploration of lived experiences and the associated relationship with physical activity and exercise for individuals with ANOCA
Kayleigh Jarrett, Robert Gordon University, United Kingdom
Background: Angina with No Obstructive Coronary Artery disease (ANOCA) is an umbrella term encompassing multiple underlying pathologies. Unlike traditional coronary artery disease (CAD), it is a complex condition, stemming from multifactorial structural and functional abnormaliti [....] » Read More
Title : A fitting pipeline to reproduce the dynamic of high complexity electrophysiology models
Hector Velasco Perez, KU Leuven, Belgium
In the last 30 years, people have devoted great efforts to generate models that reproduce the electrophysiological complexity of patient hearts. These models are referred to as digital twins and require a large number of parameters to be calibrated through experimental data and c [....] » Read More
Title : Coronary disease in women
Cristina Milagre Quadros Borges, Heart Hospital - Hcor, Brazil
Cardiovascular diseases (CVD) correspond to the main cause of death worldwide in both genders. There was an increase in the prevalence of CVD in the last 30 years in young people aged 15-49 years, of both genders with proportional mortality was higher in women throughout the peri [....] » Read More
Title : Antibodies with functionality as a new generation of translational tools designed to monitor autoimmune myocarditis at clinical and subclinical stages
Sergey Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Catalytic Abs (catAbs) are multivalent Immunoglobulins (Igs) with a capacity to hydrolyze the Antigenic (Ag) substrate. In this sense, proteolytic Abs (Ab-proteases) represent Abs to pro-vide proteolytic effects. Abs against Cardiac Myosin (CM) with proteolytic activity exhibitin [....] » Read More
Title : Perception of cardiovascular risk in women after a rehabilitation program
Maria Teresa Carvallo Marin, University of Chile, Chile
Introduction: After suffering a serious car- diovascular event (CV), cardiac rehabilitation is a process in which the patient establishes a close through a post-CV rehabilitation process. Stress was mentioned as the main CV risk factor (57%). Only 29% of respond [....] » Read More
Title : Molecular mechanisms of skeletal muscle regeneration after ischemia reperfusion injury
Yao Hua Song, Fuwai Yunnan Hospital, China
Skeletal muscle is a dynamic tissue endowed with exceptional plasticity and robust regenerative potential, which largely depends on satellite cells (SCs) residing between the muscle basement membrane and sarcolemma. The biogenesis, differentiation, and self-renewal of satellite c [....] » Read More
Title : Analysis of myocardial phase separation mechanisms driven by AI and thermodynamic laws and their clinical translation
Yangxin Li, Soochow University, China
Heart failure remains a major global cause of morbidity and mortality. A significant challengeincardiac regeneration is the inability to generate new cardiomyocytes (CMs) through cell division, whichmaybe linked to ribosome biogenesis dysfunction associated with liquid–liqu [....] » Read More
Title : Multimodal deep learning for intraoperative hemodynamic instability prediction
Vivek Vaibhav, Saraswathi Institute of Medical Sciences, India
One significant cause of perioperative morbidity and mortality is intraoperative hemodynamic instability (IHI), which includes episodes of hypotension, hypertension, and arrhythmias. Current monitoring systems mainly alert clinicians when thresholds are violated, relying heavily [....] » Read More
Title : A study of clinical profile of raised NT-proBNP in elderly patients with good LV systolic function
Nidhish Niranjan Nisty, Nisty Heart Centre, India
Introduction: NT-proBNP (N-terminal pro-B-type Natriuretic Peptide) is a blood test used mainly to diagnose and monitor heart failure. It measures a hormone released by the heart when the heart muscle is stretched due to increased pressure or fluid overload. Methodology: The a [....] » Read More
Title : Determination of significant change in right ventricular strain among patients with rheumatic mitral stenosis after percutaneous transvenous mitral commissurotomy
Maria Antonette Bernal Gelindon, Philippine Heart Center, Philippines
Introduction: Application of strain echocardiography in Rheumatic Mitral Stenosis (MS) allows new insight in evaluation of cardiac function. The aim of this paper is to describe the significant change in right ventricular (RV) strain among patients with Rheumatic MS after Percuta [....] » Read More
Title : An Uncommon case of pericarditis after transcatheter aortic valve replacement: The first reported case in Korea
Yu Jin Chung, Konkuk University Hospital, Korea, Democratic People's Republic of
Although transcatheter aortic valve replacement (TAVR) has become a favorable option for severe aortic stenosis in older patients, post-procedural complications still exist. Commonly known complications include paravalvular leakage, vascular injury, stroke, and conduction abnorma [....] » Read More
Title : Legionella pneumonia complicated by fulminant myocarditis
Faizan Butt, Rutgers Jersey City Medical Center, United States
Background: Legionella pneumophila is a well-recognized cause of severe community-acquired pneumonia, particularly in patients presenting with hyponatremia and systemic inflammatory features. While pulmonary manifestations predominate, extrapulmonary involvement may occur. Cardia [....] » Read More
Title : Impact of preoperative COVID 19 infection on myocardial injury and outcomes after aortic valve surgery in the pre vaccination era
Mohammed Hashem, Karolinska Institutet, Sweden
Background: The long-term impact of preoperative SARS-CoV-2 infection on patients undergoing surgical aortic valve replacement (SAVR) remains insufficiently defined, particularly in the pre-vaccination era. This study investigated whether previous COVID-19, determined by serology [....] » Read More